locan.analysis.accumulation_analysis

Localization-density variation analysis to characterize localization cluster.

The existence of clusters is tested by analyzing variations in cluster area and localization density within clusters. The analysis routine follows the ideas in [1] and [2].

Note

The analysis procedure is in an exploratory state and has not been fully developed and tested.

References

[1]

Baumgart F., Arnold AM., Leskovar K., Staszek K., Fölser M., Weghuber J., Stockinger H., Schütz GJ., Varying label density allows artifact-free analysis of membrane-protein nanoclusters. Nat Methods. 2016 Aug;13(8):661-4. doi: 10.1038/nmeth.3897

[2]

Spahn C., Herrmannsdörfer F., Kuner T., Heilemann M. Temporal accumulation analysis provides simplified artifact-free analysis of membrane-protein nanoclusters. Nat Methods. 2016 Nov 29;13(12):963-964. doi: 10.1038/nmeth.406

Classes

AccumulationClusterCheck([meta, ...])

Check for the presence of clusters in localization data by analyzing variations in cluster area and localization density within clusters.